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Journal article

Decreased sensitivity of 5-HT(1D) receptors in melancholic depression.

Abstract:

BACKGROUND: Brain serotonin (5-HT) function is abnormal in major depression, but the involvement of different 5-HT receptor subtypes has been little studied. The availability of selective ligands now makes it possible to test the sensitivity of 5-HT(1D) receptors in patients with depression. AIMS: The aim of the study was to use the 5-HT(1D) receptor agonist, zolmitriptan, to test the sensitivity of 5-HT(1D) receptors in patients with depression before and after treatment with selective sero...

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Publication status:
Published

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Publisher copy:
10.1192/bjp.178.5.454

Authors


Journal:
The British journal of psychiatry : the journal of mental science
Volume:
178
Issue:
5
Pages:
454-457
Publication date:
2001-05-05
DOI:
EISSN:
1472-1465
ISSN:
0007-1250
URN:
uuid:bf3c6223-4daf-42ec-98d9-62a8c5d37a9b
Source identifiers:
185776
Local pid:
pubs:185776

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