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Individual differences in response to antidepressants: a meta-analysis of placebo-controlled randomized clinical trials

Abstract:

Importance Antidepressants are commonly used to treat major depressive disorder (MDD). Antidepressant outcomes can vary based on individual differences; however, it is unclear whether specific factors determine this variability or whether it is at random.

Objective To investigate the assumption of systematic variability in symptomatic response to antidepressants and to assess whether variability is associated with MDD severity, antidepressant class...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1001/jamapsychiatry.2020.4564

Authors

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Institution:
University of Oxford
Division:
MSD
Department:
Psychiatry
Role:
Author
ORCID:
0000-0001-5179-8321


Publisher:
American Medical Association
Journal:
JAMA Psychiatry More from this journal
Volume:
78
Issue:
5
Pages:
490-497
Publication date:
2021-02-17
Acceptance date:
2020-11-30
DOI:
EISSN:
2168-6238
ISSN:
2168-622X


Language:
English
Keywords:
Pubs id:
1147518
Local pid:
pubs:1147518
Deposit date:
2020-12-02
ARK identifier:

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