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A potent halogen-bonding donor motif for anion recognition and anion template mechanical bond synthesis

Abstract:
The covalent attachment of electron deficient perfluoroaryl substituents to a bis-iodotriazole pyridinium group produces a remarkably potent halogen bonding donor motif for anion recognition in aqueous media. Such a motif also establishes halogen bonding anion templation as a highly efficient method for constructing a mechanically interlocked molecule in unprecedented near quantitative yield. The resulting bis-perfluoroaryl substituted iodotriazole pyridinium axle containing halogen bonding [2]rotaxane host exhibits exceptionally strong halide binding affinities in competitive 50 % water containing aqueous media, by a factor of at least three orders of magnitude greater in comparison to a hydrogen bonding rotaxane host analogue. These observations further champion and advance halogen bonding as a powerful tool for recognizing anions in aqueous media.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/anie.201907625

Authors

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Role:
Author
ORCID:
0000-0002-0684-1244
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Department:
CHEMISTRY
Sub department:
Inorganic Chemistry
Role:
Author
ORCID:
0000-0003-0810-9716


Publisher:
Wiley
Journal:
Angewandte Chemie International Edition More from this journal
Volume:
58
Issue:
39
Pages:
13823-13827
Publication date:
2019-09-01
Acceptance date:
2019-07-10
DOI:
EISSN:
1521-3773
ISSN:
1433-7851
Pmid:
31291498


Language:
English
Keywords:
Pubs id:
1031866
Local pid:
pubs:1031866
Deposit date:
2020-02-03
ARK identifier:

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