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Cognitive and Neurologic Rehabilitation Strategies for Central Nervous System HIV Infection

Abstract:
PURPOSE OF REVIEW: Cognitive impairment leading to disability is increasingly seen in people living with human immunodeficiency virus (PLWH). Rehabilitation can alleviate the effects of cognitive impairment upon function. The aim of this paper is to discuss the strategies that have been used in cognitive and neurologic rehabilitation in PLWH. RECENT FINDINGS: Studies examining pharmacological and non-pharmacological strategies were analysed. Medical management of HIV and co-morbidities should be optimised. Non-pharmacological strategies, including nerve stimulation techniques, exercise-based interventions, and paper and computer-based cognitive rehabilitation, have some evidence supporting their use in PLWH either as stand-alone interventions or as part of a multidisciplinary approach. Both pharmacological and non-pharmacological rehabilitation strategies have been used with PLWH. More intervention trials are needed to assess cognitive and neurological rehabilitation strategies and further evaluate their potential benefit in PLWH.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1007/s11904-020-00515-0

Authors

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Institution:
University of Oxford
Role:
Author
ORCID:
0000-0002-4811-3608
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Role:
Author
ORCID:
0000-0002-5464-9070


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Funder identifier:
https://ror.org/026zzn846


Publisher:
Springer
Journal:
Current HIV/AIDS Reports More from this journal
Volume:
17
Issue:
5
Pages:
514-521
Publication date:
2020-08-26
DOI:
EISSN:
1548-3576
ISSN:
1548-3568


Language:
English
Keywords:
Pubs id:
2320758
Local pid:
pubs:2320758
Source identifiers:
W3081398357
Deposit date:
2025-11-11
ARK identifier:
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