Journal article
Coupled enhancer and coding sequence evolution of a homeobox gene shaped leaf diversity
- Abstract:
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Here we investigate mechanisms underlying the diversification of biological forms using crucifer leaf shape as an example. We show that evolution of an enhancer element in the homeobox gene REDUCED COMPLEXITY (RCO) altered leaf shape by changing gene expression from the distal leaf blade to its base. A single amino acid substitution evolved together with this regulatory change, which reduced RCO protein stability, preventing pleiotropic effects caused by its altered gene expression. We detect...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 830.8KB)
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- Publisher copy:
- 10.1101/gad.290684.116
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Authors
Funding
+ Deutsche Forschungsgemeinschaft
More from this funder
Funding agency for:
Tsiantis, M
Grant:
SFB) 680
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Bibliographic Details
- Publisher:
- Cold Spring Harbor Laboratory Press Publisher's website
- Journal:
- Genes Development Journal website
- Volume:
- 30
- Pages:
- 2370-2375
- Publication date:
- 2016-11-16
- Acceptance date:
- 2016-10-25
- DOI:
- EISSN:
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1549-5477
- ISSN:
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0890-9369
- Source identifiers:
-
660328
Item Description
- Language:
- English
- Keywords:
- Pubs id:
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pubs:660328
- UUID:
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uuid:bee1c6b2-559b-41cc-ad3a-fbd4d62d0f59
- Local pid:
- pubs:660328
- Deposit date:
- 2016-11-29
Terms of use
- Copyright holder:
- © 2016 Vuolo, et al
- Copyright date:
- 2016
- Notes:
-
© 2016 Vuolo et al.; Published by Cold Spring Harbor Laboratory Press
This article, published in Genes & Development, is available under a Creative Commons License (Attribution 4.0 International), as described at http://creativecommons.org/licenses/by/4.0/.
- Licence:
- CC Attribution (CC BY)
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