- Abstract:
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Here we investigate mechanisms underlying the diversification of biological forms using crucifer leaf shape as an example. We show that evolution of an enhancer element in the homeobox gene REDUCED COMPLEXITY (RCO) altered leaf shape by changing gene expression from the distal leaf blade to its base. A single amino acid substitution evolved together with this regulatory change, which reduced RCO protein stability, preventing pleiotropic effects caused by its altered gene expression. We detect...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's Version
- Files:
-
-
(pdf, 830.8KB)
-
- Publisher copy:
- 10.1101/gad.290684.116
-
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- Publisher:
- Cold Spring Harbor Laboratory Press Publisher's website
- Journal:
- Genes Development Journal website
- Volume:
- 30
- Pages:
- 2370-2375
- Publication date:
- 2016-11-16
- Acceptance date:
- 2016-10-25
- DOI:
- EISSN:
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1549-5477
- ISSN:
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0890-9369
- Pubs id:
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pubs:660328
- URN:
-
uri:bee1c6b2-559b-41cc-ad3a-fbd4d62d0f59
- UUID:
-
uuid:bee1c6b2-559b-41cc-ad3a-fbd4d62d0f59
- Local pid:
- pubs:660328
- Language:
- English
- Keywords:
- Copyright holder:
- © 2016 Vuolo, et al.
- Copyright date:
- 2016
- Notes:
-
© 2016 Vuolo et al.; Published by Cold Spring Harbor Laboratory Press
This article, published in Genes & Development, is available under a Creative Commons License (Attribution 4.0 International), as described at http://creativecommons.org/licenses/by/4.0/.
Journal article
Coupled enhancer and coding sequence evolution of a homeobox gene shaped leaf diversity
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