Journal article icon

Journal article

Systematic identification of post-transcriptional regulatory modules

Abstract:

In our cells, a limited number of RNA binding proteins (RBPs) are responsible for all aspects of RNA metabolism across the entire transcriptome. To accomplish this, RBPs form regulatory units that act on specific target regulons. However, the landscape of RBP combinatorial interactions remains poorly explored. Here, we perform a systematic annotation of RBP combinatorial interactions via multimodal data integration. We build a large-scale map of RBP protein neighborhoods by generating in vivo...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Authors


More by this author
Role:
Author
ORCID:
0000-0001-9105-4028
More by this author
Institution:
University of Oxford
Role:
Author
ORCID:
0009-0008-0323-9953
More by this author
Role:
Author
ORCID:
0000-0003-0016-2643
Publisher:
Nature Research
Journal:
Nature Communications More from this journal
Volume:
15
Issue:
1
Article number:
7872
Publication date:
2024-09-09
Acceptance date:
2024-08-27
DOI:
EISSN:
2041-1723
Language:
English
Source identifiers:
2251087
Deposit date:
2024-09-10
This ORA record was generated from metadata provided by an external service. It has not been edited by the ORA Team.

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP