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Journal article

Acute molecular changes in synovial fluid following human knee injury are associated with early clinical outcomes.

Abstract:

We investigated whether molecules found to be up-regulated within hours of surgical joint destabilisation in the mouse were also elevated in the analogous human setting of acute knee injury, how this molecular response varied between individuals, and whether it related to patient-reported outcomes in the 3 months after injury.7 candidate molecules were analysed in blood and synovial fluid (SF) of 150 participants with recent structural knee injury at baseline (<8 weeks from injury) and in ...

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Publication status:
In press
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/art.39677

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Kennedy Institute for Rheumatology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Kennedy Institute for Rheumatology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
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Kennedy Trust for Rheumatology Research More from this funder
Arthritis Research UK More from this funder
Publisher:
Wiley Publisher's website
Journal:
Arthritis and Rheumatology Journal website
Publication date:
2016-03-18
Acceptance date:
2016-03-03
DOI:
EISSN:
2326-5205
ISSN:
2326-5191
Source identifiers:
611582
Language:
English
Pubs id:
pubs:611582
UUID:
uuid:bea2c5fc-8129-4e4d-b362-8d79238bf9fe
Local pid:
pubs:611582
Deposit date:
2016-05-13

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