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Magnetic resonance spectroscopy evidence of abnormal cardiac energetics in Xp21 muscular dystrophy.

Abstract:

OBJECTIVES: Our aim was to measure the cardiac phosphocreatine to adenosine triphosphate ratio (PCr/ATP) noninvasively in patients and carriers of Xp21 muscular dystrophy and to correlate the results with left ventricular (LV) function as measured by echocardiography. BACKGROUND: Duchenne and Becker muscular dystrophy (the Xp21 dystrophies) are associated with the absence or altered expression of dystrophin in cardiac and skeletal muscles. They are frequently complicated by cardiac hypertroph...

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Publication status:
Published

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Journal:
Journal of the American College of Cardiology
Volume:
36
Issue:
6
Pages:
1953-1958
Publication date:
2000-11-05
DOI:
EISSN:
1558-3597
ISSN:
0735-1097
URN:
uuid:be8a52e0-ec07-4cc1-ad99-fc849a5ab40b
Source identifiers:
106377
Local pid:
pubs:106377

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