Tolerance in T-cell clones.

Journal article

The interaction of antigen with immunologically competent cells may lead either to the induction of an immune response or to a state of antigen specific unresponsiveness complete orpartial, which is often called immunological 'tolerance'. This is believed to be a major mechanism of discrimination between self and non-self(1-3). In this review Marc Feldmann and his colleagues discuss new insights into T-cell tolerance in vivo and in vitro, and discuss their significance for our understanding of mechanisms of immune activation and regulation.

Authors: Feldmann, M; Zanders, E; Lamb, JR

• Publication status: Published
• Journal: Immunology today
• Volume: 6
• Issue: 2
• Pages: 58-62
• Publication date: 1985-02-01
• DOI: 10.1016/0167-5699(85)90049-0
• ISSN: 0167-5699
• Language: English