Journal article : Review
Definition and diagnosis of fracture-related infection
- Abstract:
- Fracture-related infection (FRI) is common and often diagnosed late.Accurate diagnosis is the beginning of effective treatment.Diagnosis can be difficult, particularly when there are no outward signs of infection.The new FRI definition, together with clear protocols for nuclear imaging, microbiological culture and histological analysis, should allow much better study design and a clearer understanding of infected fractures.In recent years, there has been a new focus on defining FRI and avoiding non-specific, poorly targeted treatment. Previous studies on FRI have often failed to define infection precisely and so are of limited value. This review highlights the essential principles of making the diagnosis and how clinical signs, serum tests, imaging, microbiology, molecular biology and histology all contribute to the diagnostic pathway.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, 668.1KB, Terms of use)
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- Publisher copy:
- 10.1302/2058-5241.5.190072
Authors
- Publisher:
- British Editorial Society of Bone and Joint Surgery
- Journal:
- EFORT Open Reviews More from this journal
- Volume:
- 5
- Issue:
- 10
- Pages:
- 614-619
- Publication date:
- 2020-10-26
- DOI:
- EISSN:
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2058-5241
- ISSN:
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2058-5241
- Pmid:
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33204503
- Language:
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English
- Keywords:
- Subtype:
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Review
- Pubs id:
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1148677
- Local pid:
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pubs:1148677
- Deposit date:
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2021-03-31
Terms of use
- Copyright holder:
- McNally et al.
- Copyright date:
- 2020
- Rights statement:
- ©2020 The author(s). This article is distributed under the terms of the Creative Commons Attribution-Non Commercial 4.0 International (CC BY-NC 4.0) licence (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed.
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