Comment on 'Estimating a modified Grubb's exponent in healthy human brains with near infrared spectroscopy and transcranial Doppler'.
The relationship between cerebral blood volume (CBV) and blood flow (CBF) has gained widespread interest because of its utility in using functional magnetic resonance imaging and optical imaging methods to estimate the cerebral metabolic rate of oxygen (CMRO(2)). A recent paper by Leung et al (2009 Physiol. Meas. 30 1-12) nicely presents measurements relating CBV to cerebral blood flow velocity (CBFV) as measured by near infrared spectroscopy and transcranial Doppler, respectively. They sugge...Expand abstract
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