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Orally administered oxygen nanobubbles enhance tumor response to sonodynamic therapy

Abstract:

Suspensions of oxygen-filled bubbles are under active investigation as potential means of relieving tissue hypoxia. Intravenous administration of large quantities of bubbles is, however, undesirable. Previous work by the authors has demonstrated that tumor oxygen levels can be increased following oral administration of phospholipid stabilized oxygen nanobubbles. The aim of this study was to determine whether this would enhance the efficacy of sonodynamic therapy (SDT), which is known to be in...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/nano.202100038

Authors


Publisher:
Wiley
Journal:
Nano Select More from this journal
Volume:
3
Issue:
2
Pages:
394-401
Publication date:
2021-06-25
Acceptance date:
2021-06-04
DOI:
EISSN:
2688-4011
Language:
English
Keywords:
Pubs id:
1184720
Local pid:
pubs:1184720
Deposit date:
2021-07-02

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