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Archaeal phylogenomics provides evidence in support of a methanogenic origin of the Archaea and a thaumarchaeal origin for the eukaryotes.

Abstract:

We have developed a machine-learning approach to identify 3537 discrete orthologue protein sequence groups distributed across all available archaeal genomes. We show that treating these orthologue groups as binary detection/non-detection data is sufficient to capture the majority of archaeal phylogeny. We subsequently use the sequence data from these groups to infer a method and substitution-model-independent phylogeny. By holding this phylogeny constrained and interrogating the intersection ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1098/rspb.2010.1427

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Institution:
University of Oxford
Division:
MPLS
Department:
Plant Sciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
Biotechnology and Biological Sciences Research Council More from this funder
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Publisher:
Royal Society Publisher's website
Journal:
Proceedings. Biological sciences / The Royal Society Journal website
Volume:
278
Issue:
1708
Pages:
1009-1018
Publication date:
2011-04-01
DOI:
EISSN:
1471-2954
ISSN:
0962-8452
Source identifiers:
83825
Language:
English
Keywords:
Pubs id:
pubs:83825
UUID:
uuid:bd3c7bf9-4ab1-4a6a-ba2e-9b9709de0e96
Local pid:
pubs:83825
Deposit date:
2013-03-20

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