Neuroscience & Neuroimaging Research Collection

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Glycodeoxycholic and deoxycholic bile acids impair recognition and spatial memory in adult mice, and reduce central CREB-BDNF signaling and cytokine expression with neuroanatomical specificity

Documentation:: These data were created over the past 18 months as part of a UKRI grant. Mouse behaviour and brain gene expression data are in an SPSS file. Metagenomic data accrued from faecal samples and bile acid levels in plasma from mice included in the study are in Excel or CSV format so they can be used in most analysis packages, such as 'R'. A Word document detailing all the methods is also provided.

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APA Style

Burnet, P., Garcia, A., Trivedi, D., Anthony, D., & Swann, J. (2025). Glycodeoxycholic and deoxycholic bile acids impair recognition and spatial memory in adult mice, and reduce central CREB-BDNF signaling and cytokine expression with neuroanatomical specificity. University of Oxford.

MLA Style

Burnet, P, et al. Glycodeoxycholic and Deoxycholic Bile Acids Impair Recognition and Spatial Memory in Adult Mice, and Reduce Central CREB-BDNF Signaling and Cytokine Expression with Neuroanatomical Specificity. University of Oxford, 2025.

Chicago Style

Burnet, P, A Garcia, D Trivedi, D Anthony, and J Swann. 2025. Glycodeoxycholic and Deoxycholic Bile Acids Impair Recognition and Spatial Memory in Adult Mice, and Reduce Central CREB-BDNF Signaling and Cytokine Expression with Neuroanatomical Specificity. University of Oxford.
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Files:: Garcia_Bile Acids&Cognition.zip

(zip, 2.9MB, Terms of use)

Authors/Creators

+ Burnet, P More by this author/creator

Institution:: University of Oxford
Division:: MSD
Department:: Psychiatry
Role:: Creator
ORCID:: 0000-0002-6374-8054

+ Garcia, A More by this author/creator

Role:: Creator

+ Trivedi, D More by this author/creator

Role:: Creator

+ Anthony, D More by this author/creator

Role:: Creator

+ Swann, J More by this author/creator

Role:: Creator

+ Biotechnology and Biological Sciences Research Council More from this funder

Funder identifier:: https://ror.org/00cwqg982
Grant:: BB/W000954/1

Publisher:: University of Oxford
Publication date:: 2025
DOI:: 10.5287/ora-5r08j6x1e

Language:: English
Keywords:: cognitive impairment

glutamate

inflammatory

gut-brain axis
Pubs id:: 2335007
UUID:: uuid_bd29f7e0-37b7-412a-bb12-0fcb85ca9d1a
Local pid:: pubs:2335007
Deposit date:: 2025-11-24
ARK identifier:: ark:/29072/ora_bd29f7e037b7412abb120fcb85ca9d1a

Terms of use

Copyright date:: 2025

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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