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Journal article

Rapid chiral assembly of rigid DNA building blocks for molecular nanofabrication.

Abstract:

Practical components for three-dimensional molecular nanofabrication must be simple to produce, stereopure, rigid, and adaptable. We report a family of DNA tetrahedra, less than 10 nanometers on a side, that can self-assemble in seconds with near-quantitative yield of one diastereomer. They can be connected by programmable DNA linkers. Their triangulated architecture confers structural stability; by compressing a DNA tetrahedron with an atomic force microscope, we have measured the axial comp...

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Publication status:
Published

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Publisher copy:
10.1126/science.1120367

Authors


Goodman, RP More by this author
Schaap, IA More by this author
Tardin, CF More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Physics, Condensed Matter Physics
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Journal:
Science (New York, N.Y.)
Volume:
310
Issue:
5754
Pages:
1661-1665
Publication date:
2005-12-05
DOI:
EISSN:
1095-9203
ISSN:
0036-8075
URN:
uuid:bcc73583-8de6-4337-9a1b-e5452edb25ff
Source identifiers:
6791
Local pid:
pubs:6791

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