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In vitro and in vivo methods to determine the interactions of osteogenic cells with biomaterials.

Abstract:

To assess new biomaterials for possible use as bone graft substitutes, a number of techniques allow interactions with osteoblastic cells to be studied, with respect to effects on proliferation and differentiation of osteoprogenitors. In vitro models include the use of bone explant cultures, fetal rat calvarial-derived osteoblast cells, primary stromal populations, transformed and non-transformed cell lines and immortalized osteoblast cell lines. However, these assessments are limited by the e...

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Publication status:
Published

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Publisher copy:
10.1023/a:1008931607002

Authors


Oreffo, RO More by this author
Triffitt, JT More by this author
Publisher:
Kluwer Academic Publishers
Journal:
Journal of materials science. Materials in medicine
Volume:
10
Issue:
10/11
Pages:
607-611
Publication date:
1999
DOI:
EISSN:
1573-4838
ISSN:
0957-4530
URN:
uuid:bcc2e79a-1fb6-4674-ba9a-6f0daafad907
Source identifiers:
108812
Local pid:
pubs:108812
Language:
English

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