Background: Interferon Inducible Transmembrane 3 (IFITM3) is a key factor in interferon pathway and it involves host's immune response against multiple viruses. IFITM3 rs12252-C was associated with severe influenza virus infection in several studies, however whether this association is universal to all types of influenza virus or diverse ethnic populations remain controversial.Expand abstract
Method: A case-control genetic association study was performed from September 2013 to Apri...
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- Peer reviewed
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- Frontiers Media Publisher's website
- Frontiers in Cellular and Infection Microbiology Journal website
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- Pan et al.
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- © 2017 Pan, Yang, Dong, Zhang, Shi, Peng, Cui, Zhang, Lu, Liu, Wu and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).
IFITM3 Rs12252-C Variant Increases Potential Risk for Severe Influenza Virus Infection in Chinese Population.
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