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Invasive Streptococcus agalactiae ST283 infection after fish consumption in two sisters, Lao PDR

Abstract:

Background: Streptococcus agalactiae is a normal commensal of the human gastro-intestinal and female genital tracts. It causes serious disease in neonates and pregnant women, as well as non-pregnant adults. Food-borne outbreaks have also been described. A link between invasive Group B streptococcus (GBS) infection in humans caused by S. agalactiae serotype III-4, sequence type 283 (ST283) and the consumption of raw fresh-water fish was first described in Singapore in 2015.

Case presentation: We report the simultaneous occurrence of acute fever and myalgia in two sisters who were visiting Laos. Both were found to have invasive GBS ST283 infection, confirmed by blood culture. Infection was temporally linked to fish consumption. They responded well to intravenous antibiotics within 48 hours.

Conclusions: Food-borne transmission of Streptococcus agalactiae is an important and under-recognised source of serious human disease throughout Southeast Asia and possibly beyond.

Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.12688/wellcomeopenres.17804.2

Authors


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Role:
Author
ORCID:
0000-0002-8801-5738


Publisher:
F1000 Research Ltd
Journal:
Wellcome Open Research More from this journal
Volume:
7
Article number:
148
Publication date:
2022-05-06
Acceptance date:
2022-05-06
DOI:
EISSN:
2398-502X


Language:
English
Keywords:
Pubs id:
1312340
Local pid:
pubs:1312340
Deposit date:
2023-03-08

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