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Assessing the direct effects of deep brain stimulation using embedded axon models.

Abstract:

To better understand the spatial extent of the direct effects of deep brain stimulation (DBS) on neurons, we implemented a geometrically realistic finite element electrical model incorporating anisotropic and inhomogenous conductivities. The model included the subthalamic nucleus (STN), substantia nigra (SN), zona incerta (ZI), fields of Forel H2 (FF), internal capsule (IC) and Medtronic 3387/3389 electrode. To quantify the effects of stimulation, we extended previous studies by using multi-c...

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Publisher copy:
10.1088/1741-2560/4/2/011

Authors


Sotiropoulos, SN More by this author
Steinmetz, PN More by this author
Journal:
Journal of neural engineering
Volume:
4
Issue:
2
Pages:
107-119
Publication date:
2007-06-05
DOI:
EISSN:
1741-2552
ISSN:
1741-2560
URN:
uuid:bc7ab839-dbe9-4d20-a98e-75e270ac258e
Source identifiers:
243067
Local pid:
pubs:243067

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