Safety of age-dosed, single low-dose primaquine in children with glucose-6-phosphate dehydrogenase deficiency who are infected with Plasmodium falciparum in Uganda and the Democratic Republic of the Congo: a randomised, double-blind, placebo-controlled, non-inferiority trial

Taylor, WR; Olupot-Olupot, P; Onyamboko, MA; Peerawaranun, P; Weere, W; Namayanja, C; Onyas, P; Titin, H; Baseke, J; Muhindo, R; Kayembe, DK; Ndjowo, PO; Basara, BB; Bongo, GS; Okalebo, CB; Abongo, G; Uyoga, S; Williams, TN; Taya, C; Dhorda, M; Tarning, J; Dondorp, AM; Waithira, N; Fanello, C; Maitland, K; Mukaka, M; Day, NJP

Journal article

Safety of age-dosed, single low-dose primaquine in children with glucose-6-phosphate dehydrogenase deficiency who are infected with Plasmodium falciparum in Uganda and the Democratic Republic of the Congo: a randomised, double-blind, placebo-controlled, non-inferiority trial

Abstract:: Background: WHO recommends gametocytocidal, single low-dose primaquine for blocking the transmission of Plasmodium falciparum; however, safety concerns have hampered the implementation of this strategy in sub-Saharan Africa. We aimed to investigate the safety of age-dosed, single low-dose primaquine in children from Uganda and the Democratic Republic of the Congo.

Methods: We conducted this randomised, double-blind, placebo-c...
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Publication status:: Published

Peer review status:: Peer reviewed

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APA Style

Taylor, W. R., Olupot-Olupot, P., Onyamboko, M. A., Peerawaranun, P., Weere, W., Namayanja, C., Onyas, P., Titin, H., Baseke, J., Muhindo, R., Kayembe, D. K., Ndjowo, P. O., Basara, B. B., Bongo, G. S., Okalebo, C. B., Abongo, G., Uyoga, S., Williams, T. N., Taya, C., … Day, N. J. P. (2022). Safety of age-dosed, single low-dose primaquine in children with glucose-6-phosphate dehydrogenase deficiency who are infected with Plasmodium falciparum in Uganda and the Democratic Republic of the Congo: a randomised, double-blind, placebo-controlled, non-inferiority trial. Lancet Infectious Diseases, 23(4), 471–483.

MLA Style

Taylor, W. R., et al. “Safety of Age-Dosed, Single Low-Dose Primaquine in Children with Glucose-6-Phosphate Dehydrogenase Deficiency Who Are Infected with Plasmodium Falciparum in Uganda and the Democratic Republic of the Congo: a Randomised, Double-Blind, Placebo-Controlled, Non-Inferiority Trial.” Lancet Infectious Diseases, vol. 23, no. 4, Elsevier, 2022, pp. 471–83.

Chicago Style

Taylor, WR, P Olupot-Olupot, MA Onyamboko, P Peerawaranun, W Weere, C Namayanja, P Onyas, et al. 2022. “Safety of Age-Dosed, Single Low-Dose Primaquine in Children with Glucose-6-Phosphate Dehydrogenase Deficiency Who Are Infected with Plasmodium Falciparum in Uganda and the Democratic Republic of the Congo: a Randomised, Double-Blind, Placebo-Controlled, Non-Inferiority Trial.” Lancet Infectious Diseases 23 (4): 471–83.
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