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Journal article

Virotherapy--cancer targeted pharmacology.

Abstract:

Building on their success in vaccination, many groups are now exploring the use of viruses as anticancer agents. In general, viral therapeutics provide the possibility to express anticancer proteins directly at the tumour site, decreasing exposure to normal tissue during delivery and maximising therapeutic index. Some viruses are also 'oncolytic', either naturally or by design, and these agents function to kill cancer cells selectively before spreading to infect adjacent cells and repeat the ...

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Publication status:
Published

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Journal:
Drug discovery today
Volume:
17
Issue:
5-6
Pages:
215-220
Publication date:
2012-03-05
DOI:
EISSN:
1878-5832
ISSN:
1359-6446
URN:
uuid:bb9a3635-30d7-4410-8bac-4b1dcd6baddc
Source identifiers:
222334
Local pid:
pubs:222334

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