Journal article
Microbial-host co-metabolites are prodromal markers predicting phenotypic heterogeneity in behavior, obesity, and impaired glucose tolerance
- Abstract:
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The influence of the gut microbiome on metabolic and behavioral traits is widely accepted, though the microbiome-derived metabolites involved remain unclear. We carried out untargeted urine 1H-NMR spectroscopy-based metabolic phenotyping in an isogenic C57BL/6J mouse population (n = 50) and show that microbial-host co-metabolites are prodromal (i.e., early) markers predicting future divergence in metabolic (obesity and glucose homeostasis) and behavioral (anxiety and activity) outcomes with 9...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 4.6MB, Terms of use)
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- Publisher copy:
- 10.1016/j.celrep.2017.06.039
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Bibliographic Details
- Publisher:
- Cell Press
- Journal:
- Cell Reports More from this journal
- Volume:
- 20
- Issue:
- 1
- Pages:
- 136-148
- Publication date:
- 2017-07-05
- Acceptance date:
- 2017-06-12
- DOI:
- ISSN:
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2211-1247
- Pmid:
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28683308
Item Description
- Language:
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English
- Keywords:
- Pubs id:
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pubs:707912
- UUID:
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uuid:bb30e12a-8ecc-4451-9fa6-5cfb552927b3
- Local pid:
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pubs:707912
- Source identifiers:
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707912
- Deposit date:
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2018-01-02
Terms of use
- Copyright holder:
- Dumas et al
- Copyright date:
- 2017
- Notes:
-
Copyright © 2017 The Authors.
This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
- Licence:
- CC Attribution (CC BY)
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