Journal article

A new class of highly potent, broadly neutralizing antibodies isolated from viremic patients infected with dengue virus

Abstract:: Dengue is a rapidly emerging, mosquito-borne viral infection, with an estimated 400 million infections occurring annually. To gain insight into dengue immunity, we characterized 145 human monoclonal antibodies (mAbs) and identified a previously unknown epitope, the envelope dimer epitope (EDE), that bridges two envelope protein subunits that make up the 90 repeating dimers on the mature virion. The mAbs to EDE were broadly reactive across the dengue serocomplex...
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Publication status:: Published

Peer review status:: Peer reviewed

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APA Style

Dejnirattisai, W., Wongwiwat, W., Supasa, S., Zhang, X., Dai, X., Rouvinski, A., Jumnainsong, A., Edwards, C., Quyen, N., Duangchinda, T., Grimes, J., Tsai, W., Lai, C., Wang, W., Malasit, P., Farrar, J., Farrar, J., Simmons, C., Zhou, Z., … Screaton, G. (2014). A new class of highly potent, broadly neutralizing antibodies isolated from viremic patients infected with dengue virus. Nature Immunology, 16(2), 170–177.

MLA Style

Dejnirattisai, W., et al. “A New Class of Highly Potent, Broadly Neutralizing Antibodies Isolated from Viremic Patients Infected with Dengue Virus.” Nature Immunology, vol. 16, no. 2, Springer Nature, 2014, pp. 170–77.

Chicago Style

Dejnirattisai, W, W Wongwiwat, S Supasa, X Zhang, X Dai, A Rouvinski, A Jumnainsong, et al. 2014. “A New Class of Highly Potent, Broadly Neutralizing Antibodies Isolated from Viremic Patients Infected with Dengue Virus.” Nature Immunology 16 (2): 170–77.
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Publisher copy:: 10.1038/ni.3058

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+ Dejnirattisai, W More by this author

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University of Oxford

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MSD

Department:

NDM

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Author

+ Wongwiwat, W More by this author

Role:

Author

+ Supasa, S More by this author

Role:

Author

+ Zhang, X More by this author

Role:

Author

+ Dai, X More by this author

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Funding

+ 095541/Wellcome Trust More from this funder

+ /Medical Research Council More from this funder

+ S10 RR023057/NCRR NIH HHS More from this funder

+ S10 OD018111/NIH HHS More from this funder

+ R01 GM071940/NIGMS NIH HHS More from this funder

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Bibliographic Details

Publisher:: Springer Nature
Journal:: Nature Immunology More from this journal
Volume:: 16
Issue:: 2
Pages:: 170–177
Publication date:: 2014-12-15
Acceptance date:: 2014-11-18
DOI:: 10.1038/ni.3058
EISSN:: 1529-2916
ISSN:: 1529-2908
Pmid:: 25501631

Item Description

Language:: English
Keywords:: SBTMR
Pubs id:: pubs:499670
UUID:: uuid:bab75f6a-8b3c-42e8-9bee-638edc381e63
Local pid:: pubs:499670
Source identifiers:: 499670
Deposit date:: 2017-02-22

Terms of use

Copyright holder:: Nature America
Copyright date:: 2014
Notes:: © 2015 Nature America, Inc. All rights reserved

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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