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Chimpanzee adenovirus vaccine provides multispecies protection against Rift Valley Fever

Abstract:

Rift Valley Fever virus (RVFV) causes recurrent outbreaks of acute life-threatening human and livestock illness in Africa and the Arabian Peninsula. No licensed vaccines are currently available for humans and those widely used in livestock have major safety concerns. A 'One Health' vaccine development approach, in which the same vaccine is co-developed for multiple susceptible species, is an attractive strategy for RVFV. Here, we utilized a replication-deficient chimpanzee adenovirus vaccine ...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1038/srep20617

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, NDM, Jenner Institute
Gesharisha, J More by this author
Otingah, K More by this author
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Funding agency for:
Warimwe, GM
University of Oxford More from this funder
Publisher:
Nature Publishing Group Publisher's website
Journal:
Scientific Reports Journal website
Volume:
6
Pages:
20617
Publication date:
2016-02-05
DOI:
EISSN:
2045-2322
URN:
uuid:baa9b526-15cd-468c-ac7c-0a599c6319a2
Source identifiers:
600597
Local pid:
pubs:600597
Language:
English

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