Journal article
DOMINO-AD protocol: donepezil and memantine in moderate to severe Alzheimer's disease - a multicentre RCT.
- Abstract:
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BACKGROUND: Alzheimer's disease (AD) is the commonest cause of dementia. Cholinesterase inhibitors, such as donepezil, are the drug class with the best evidence of efficacy, licensed for mild to moderate AD, while the glutamate antagonist memantine has been widely prescribed, often in the later stages of AD. Memantine is licensed for moderate to severe dementia in AD but is not recommended by the England and Wales National Institute for Health and Clinical Excellence. However, there is little...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 293.6KB)
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- Publisher copy:
- 10.1186/1745-6215-10-57
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Authors
Funding
Medical Research Council
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Alzheimer's Society
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Bibliographic Details
- Publisher:
- BioMed Central Publisher's website
- Journal:
- Trials Journal website
- Volume:
- 10
- Issue:
- 1
- Pages:
- 57
- Publication date:
- 2009-01-01
- DOI:
- EISSN:
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1745-6215
- ISSN:
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1745-6215
- Source identifiers:
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112086
Item Description
- Language:
- English
- Keywords:
- Pubs id:
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pubs:112086
- UUID:
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uuid:b9f73fa7-7012-44e1-873d-e9e835a2ebcb
- Local pid:
- pubs:112086
- Deposit date:
- 2012-12-19
Terms of use
- Copyright holder:
- Jones et al
- Copyright date:
- 2009
- Notes:
-
Copyright © 2009 Jones et al.
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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