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A randomised placebo-controlled trial of oral hydrocortisone for treating tobacco withdrawal symptoms.

Abstract:

RATIONALE: Many smokers experience a decline in cortisol to sub-normal levels during the first days of smoking cessation. A greater decline in cortisol is associated with more intense cigarette withdrawal symptoms, urge to smoke and relapse to smoking. Findings from an uncontrolled study suggest that glucocorticoids could ameliorate cigarette withdrawal. OBJECTIVES: We investigated whether taking oral hydrocortisone would reduce withdrawal symptoms and the desire to smoke on the first day of...

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Publisher copy:
10.1007/s00213-011-2191-x

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Institution:
University of Oxford
Department:
Oxford, MSD, Primary Care Health Sciences
Role:
Author
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Journal:
Psychopharmacology
Volume:
216
Issue:
1
Pages:
43-51
Publication date:
2011-07-05
DOI:
EISSN:
1432-2072
ISSN:
0033-3158
URN:
uuid:b9f0b810-e883-4a60-8dfa-0d4a187dfdaa
Source identifiers:
351523
Local pid:
pubs:351523

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