Emergence in Vietnam of Streptococcus pneumoniae resistant to multiple antimicrobial agents as a result of dissemination of the multiresistant Spain(23F)-1 clone.

Journal article

Surveillance for Streptococcus pneumoniae resistant to penicillin and other antimicrobial agents is necessary to define the optimal empirical antibiotic therapy for meningitis in resource-poor countries such as Vietnam. The clinical and microbiological features of 100 patients admitted to the Centre for Tropical Diseases in Ho Chi Minh City, Vietnam, between 1993 and 2002 with invasive pneumococcal disease were studied. A penicillin-nonsusceptible pneumococcus (MIC, > or =0.1 micro g/ml) w...

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Authors: Parry, C; Duong, N; Zhou, J; Mai, N; Diep, T

• Publication status: Published
• Journal: Antimicrobial agents and chemotherapy
• Volume: 46
• Issue: 11
• Pages: 3512-3517
• Publication date: 2002-11-01
• DOI: 10.1128/aac.46.11.3512-3517.2002
• EISSN: 1098-6596
• ISSN: 0066-4804
• Language: English
• Keywords: Streptococcus pneumoniae; Adult; Anti-Inflammatory Agents; Microbial Sensitivity Tests; Dexamethasone; Humans; Aged, 80 and over; Drug Resistance, Multiple, Bacterial; Adolescent; Middle Aged; Penicillin Resistance; Serotyping; Male; Vietnam; Pneumococcal Infections; Double-Blind Method; Aged; Female