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Journal article

Neuronal genes deregulated in Cornelia de Lange Syndrome respond to removal and re-expression of cohesin

Abstract:

El síndrome Cornelia de Lange (SCdL, OMIM #122470, #300590, #300882, #610759 y #614701) es un trastorno raro del neurodesarrollo que afecta a múltiples aparatos y sistemas, caracterizado por una facies distintiva, baja talla, anomalías en las extremidades y discapacidad intelectual. Desde la identificación del primer gen causal, NIPBL, hace veinte años, se han descrito multitud de variantes genéticas y se han asociado otros siete genes, la mayoría relacionados al complejo cohesina. Sin embarg...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/s41467-021-23141-9

Authors

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Role:
Author
ORCID:
0000-0003-0228-5081
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Role:
Author
ORCID:
0000-0001-5253-7369
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Role:
Author
ORCID:
0000-0002-2241-2175
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Role:
Author
ORCID:
0000-0001-5350-266X


Publisher:
Nature Research
Journal:
Nature Communications More from this journal
Volume:
12
Issue:
1
Pages:
2919-2919
Publication date:
2021-05-18
DOI:
EISSN:
2041-1723
ISSN:
2041-1723


Language:
Spanish
Keywords:
Pubs id:
2373722
Local pid:
pubs:2373722
Source identifiers:
W3163271254
Deposit date:
2026-02-15
ARK identifier:
This ORA record was generated from metadata provided by an external service. It has not been edited by the ORA Team.

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