- Abstract:
-
Sensitive and reliable methods are required for the assessment of oxidative DNA damage, which can result from reactive oxygen species that are generated endogenously from cellular metabolism and inflammatory responses, or by exposure to exogenous agents. The development of a liquid chromatography/tandem mass spectrometry (LC/MS/MS) selected reaction monitoring (SRM) method is described, that utilises online column-switching valve technology for the simultaneous determination of two DNA adduct...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1002/rcm.3866
-
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- Journal:
- Rapid communications in mass spectrometry : RCM
- Volume:
- 23
- Issue:
- 1
- Pages:
- 151-160
- Publication date:
- 2009-01-05
- DOI:
- EISSN:
-
1097-0231
- ISSN:
-
0951-4198
- URN:
-
uuid:b8f09317-5b8c-463c-bc7d-6204481f28f5
- Source identifiers:
-
132103
- Local pid:
- pubs:132103
- Copyright date:
- 2009
Journal article
Simultaneous determination of 8-oxo-2'-deoxyguanosine and 8-oxo-2'-deoxyadenosine in DNA using online column-switching liquid chromatography/tandem mass spectrometry.
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