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Identification and characterization of peripheral T-cell lymphoma-associated SEREX antigens.

Abstract:

Peripheral T-cell lymphomas (PTCL) are generally less common and pursue a more aggressive clinical course than B-cell lymphomas, with the T-cell phenotype itself being a poor prognostic factor in adult non-Hodgkin lymphoma (NHL). With notable exceptions such as ALK(+) anaplastic large cell lymphoma (ALCL, ALK+), the molecular abnormalities in PTCL remain poorly characterised. We had previously identified circulating antibodies to ALK in patients with ALCL, ALK(+). Thus, as a strategy to ident...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1371/journal.pone.0023916

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Institution:
University of Oxford
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Institution:
University of Oxford
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Institution:
University of Oxford
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Institution:
University of Oxford
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Julian Starmer-Smith Memorial Fund More from this funder
Leukaemia and Lymphoma Research More from this funder
Publisher:
Public Library of Science Publisher's website
Journal:
PloS one Journal website
Volume:
6
Issue:
8
Article number:
e23916
Publication date:
2011-01-01
DOI:
EISSN:
1932-6203
Source identifiers:
179491

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