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Journal article

The informed consent process in health research with under-served populations: a realist review protocol

Abstract:
Background:
The informed consent process aims to provide potential participants with information about health research that enables them to make an informed decision as to whether they choose to participate, or not. However, it remains unclear as to whether the process is effective for those who are under-served in health research. It is a pivotal issue within health research that the diversity of people who participate is broadened. The National Institute for Health Research (NIHR) pledges to support equality, diversity and inclusion, actively creating opportunities for all citizens whom are eligible, to take part in health research.
Methods:
In order to understand how the informed consent process for under-served populations in health research works, under what circumstances and in what respects, a realist review approach will be undertaken. Searches will be carried out using electronic databases (EMBASE, MEDLINE, Web of Science and PsycINFO), along with selected websites and grey literature. Development of initial rough programme theory(ies) will lead to a more refined programme theory that will provide an explanation of context, mechanism and outcomes. Stakeholder involvement by NIHR (Public) Research Champions, health professionals and clinical academics will provide expert opinion about concepts and programme theory.
Discussion:
Findings of this realist review will highlight how the informed consent process in health research affects the experience and decision-making process of potential participants from under-served populations. They will be written up in accordance with RAMESES guidelines and disseminated to patients and the public, health researchers, health professionals and policymakers through peer-reviewed publication, presentations and discussions. The review will contribute to our understanding of the mechanisms that cause both positive and negative outcomes in the informed consent process for those whom are often under-represented in health research to inform policy, study design and delivery.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/s13643-021-01652-2

Authors

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Institution:
University of Oxford
Division:
MSD
Department:
Primary Care Health Sciences
Role:
Author
ORCID:
0000-0002-8482-655X



Publisher:
BioMed Central
Journal:
Systematic Reviews More from this journal
Volume:
10
Issue:
1
Article number:
103
Publication date:
2021-04-09
Acceptance date:
2021-03-29
DOI:
EISSN:
2046-4053


Language:
English
Keywords:
Pubs id:
2128989
Local pid:
pubs:2128989
Deposit date:
2025-06-09
ARK identifier:

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