Journal article
Identification and characterization of proximal promoter polymorphisms in the human concentrative nucleoside transporter 2 (SLC28A2).
- Abstract:
-
The human concentrative nucleoside transporter 2 (CNT2) plays an important role in the absorption, disposition, and biological effects of endogenous nucleosides and nucleoside analog drugs. We identified genetic variation in the basal promoter region of CNT2 and characterized the function of the variants. We screened DNA from an ethnically diverse population and identified five basal promoter variants in CNT2. Three major haplotypes in the CNT2 basal promoter region were identified and were f...
Expand abstract
- Publication status:
- Published
Actions
Authors
Bibliographic Details
- Journal:
- Journal of pharmacology and experimental therapeutics
- Volume:
- 328
- Issue:
- 3
- Pages:
- 699-707
- Publication date:
- 2009-03-01
- DOI:
- EISSN:
-
1521-0103
- ISSN:
-
0022-3565
- Source identifiers:
-
68180
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:68180
- UUID:
-
uuid:b8b61b40-2bb1-415e-8079-de19b0471a30
- Local pid:
- pubs:68180
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2009
If you are the owner of this record, you can report an update to it here: Report update to this record