Journal article
Ex vivo phenotype and frequency of influenza virus-specific CD4 memory T cells.
- Abstract:
- Recent advances in class II tetramer staining technology have allowed reliable direct ex vivo visualization of antigen-specific CD4 T cells. In order to define the frequency and phenotype of a prototype response to a nonpersistent pathogen, we have used such techniques to analyze influenza virus-specific memory CD4 T cells directly from blood. These responses are stably detectable ex vivo at low frequencies (range, 0.00012 to 0.0061% of CD4 T cells) and display a distinct "central memory" CD62L(+) phenotype.
- Publication status:
- Published
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Bibliographic Details
- Journal:
- Journal of virology More from this journal
- Volume:
- 78
- Issue:
- 13
- Pages:
- 7284-7287
- Publication date:
- 2004-07-01
- DOI:
- EISSN:
-
1098-5514
- ISSN:
-
0022-538X
Item Description
- Language:
-
English
- Keywords:
- Pubs id:
-
pubs:29942
- UUID:
-
uuid:b8aafce2-da8e-4449-af9c-323fc63c633e
- Local pid:
-
pubs:29942
- Source identifiers:
-
29942
- Deposit date:
-
2012-12-19
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- Copyright date:
- 2004
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