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Journal article

Ex vivo phenotype and frequency of influenza virus-specific CD4 memory T cells.

Abstract:
Recent advances in class II tetramer staining technology have allowed reliable direct ex vivo visualization of antigen-specific CD4 T cells. In order to define the frequency and phenotype of a prototype response to a nonpersistent pathogen, we have used such techniques to analyze influenza virus-specific memory CD4 T cells directly from blood. These responses are stably detectable ex vivo at low frequencies (range, 0.00012 to 0.0061% of CD4 T cells) and display a distinct "central memory" CD62L(+) phenotype.
Publication status:
Published

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Publisher copy:
10.1128/jvi.78.13.7284-7287.2004

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Journal:
Journal of virology More from this journal
Volume:
78
Issue:
13
Pages:
7284-7287
Publication date:
2004-07-01
DOI:
EISSN:
1098-5514
ISSN:
0022-538X
Language:
English
Keywords:
Pubs id:
pubs:29942
UUID:
uuid:b8aafce2-da8e-4449-af9c-323fc63c633e
Local pid:
pubs:29942
Source identifiers:
29942
Deposit date:
2012-12-19

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