Journal article
The role of estrogen in the control of rat osteocyte apoptosis.
- Abstract:
-
We have previously shown that estrogen withdrawal by gonadotrophin-releasing hormone analogs (GnRHa) induces osteocyte death via apoptosis in human bone. Although it is likely that the increase in osteocyte death via apoptosis was related to the loss of estrogen, these experiments could not rule out a direct role for the GnRHa. Therefore, in this study, we have used a rat model of ovariectomy (OVX) to determine whether the effect of estrogen withdrawal extends to other species and to clarify ...
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- Publication status:
- Published
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- Publisher copy:
- 10.1359/jbmr.1998.13.8.1243
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Authors
Bibliographic Details
- Journal:
- Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
- Volume:
- 13
- Issue:
- 8
- Pages:
- 1243-1250
- Publication date:
- 1998-08-01
- DOI:
- EISSN:
-
1523-4681
- ISSN:
-
0884-0431
- Source identifiers:
-
473777
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:473777
- UUID:
-
uuid:b85a1d1b-0b3d-490f-afd5-36ab7f72cbc2
- Local pid:
- pubs:473777
- Deposit date:
- 2014-07-05
Terms of use
- Copyright date:
- 1998
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