Origins and evolutionary genomics of the 2009 swine-origin H1N1 influenza A epidemic.

Journal article

In March and early April 2009, a new swine-origin influenza A (H1N1) virus (S-OIV) emerged in Mexico and the United States. During the first few weeks of surveillance, the virus spread worldwide to 30 countries (as of May 11) by human-to-human transmission, causing the World Health Organization to raise its pandemic alert to level 5 of 6. This virus has the potential to develop into the first influenza pandemic of the twenty-first century. Here we use evolutionary analysis to estimate the tim...

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Authors: Smith, G; Vijaykrishna, D; Bahl, J; Lycett, S; Worobey, M

• Publication status: Published
• Journal: Nature
• Volume: 459
• Issue: 7250
• Pages: 1122-1125
• Publication date: 2009-06-01
• DOI: 10.1038/nature08182
• EISSN: 1476-4687
• ISSN: 0028-0836
• Language: English
• Keywords: Animals; Orthomyxoviridae Infections; Influenza A Virus, H1N1 Subtype; Disease Outbreaks; Swine; Humans; Swine Diseases; Phylogeny; Reassortant Viruses; Influenza, Human; Evolution, Molecular; Molecular Sequence Data; Genome, Viral; Time Factors