Journal article
Defining a protective epitope on factor H binding protein, a key meningococcal virulence factor and vaccine antigen.
- Abstract:
-
Mapping of epitopes recognized by functional monoclonal antibodies (mAbs) is essential for understanding the nature of immune responses and designing improved vaccines, therapeutics, and diagnostics. In recent years, identification of B-cell epitopes targeted by neutralizing antibodies has facilitated the design of peptide-based vaccines against highly variable pathogens like HIV, respiratory syncytial virus, and Helicobacter pylori; however, none of these products has yet progressed into cli...
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- Publication status:
- Published
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- Publisher copy:
- 10.1073/pnas.1222845110
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Bibliographic Details
- Journal:
- Proceedings of the National Academy of Sciences of the United States of America
- Volume:
- 110
- Issue:
- 9
- Pages:
- 3304-3309
- Publication date:
- 2013-02-08
- DOI:
- EISSN:
-
1091-6490
- ISSN:
-
0027-8424
- Source identifiers:
-
384332
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:384332
- UUID:
-
uuid:b8232504-35d3-43ab-93cb-74cf2d22bd50
- Local pid:
- pubs:384332
- Deposit date:
- 2013-11-16
Terms of use
- Copyright date:
- 2013
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