Parallel molecular evolution and adaptation are important phenomena commonly observed in viruses. Here, we exploit parallel molecular evolution to understand virulence evolution in avian influenza viruses (AIV). Highly-pathogenic AIVs evolve independently from low-pathogenic ancestors via acquisition of polybasic cleavage sites. Why some AIV lineages but not others evolve in this way is unknown. We hypothesise that the parallel emergence of highly-pathogenic AIV may be facilitated by permissi...Expand abstract
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- A Publisher Correction to this article was published on 23 November 2020 and is available online at: https://doi.org/10.1038/s41467-020-20006-5
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Parallel evolution in the emergence of highly pathogenic avian influenza a viruses
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