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Genetic determinants of height growth assessed longitudinally from infancy to adulthood in the northern Finland birth cohort 1966.

Abstract:

Recent genome-wide association (GWA) studies have identified dozens of common variants associated with adult height. However, it is unknown how these variants influence height growth during childhood. We derived peak height velocity in infancy (PHV1) and puberty (PHV2) and timing of pubertal height growth spurt from parametric growth curves fitted to longitudinal height growth data to test their association with known height variants. The study consisted of N = 3,538 singletons from the prosp...

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Publication status:
Published

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Publisher copy:
10.1371/journal.pgen.1000409

Authors


Bennett, AJ More by this author
Millwood, IY More by this author
Molitor, J More by this author
O'Reilly, PF More by this author
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Journal:
PLoS genetics
Volume:
5
Issue:
3
Pages:
e1000409
Publication date:
2009-03-05
DOI:
EISSN:
1553-7404
ISSN:
1553-7390
URN:
uuid:b80d1e8f-18fd-480d-87c8-55883c1ec22e
Source identifiers:
13754
Local pid:
pubs:13754

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