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Spironolactone is an effective and well tolerated systemic antiandrogen therapy for Hirsute women.

Abstract:

We treated 22 hirsute women with spironolactone in an open trial to determine whether it caused objective changes in hair growth. Among them, 18 women completed 12 months therapy with 200 mg spironolactone daily. During this period, the mean daily linear growth rates of hair on the face, abdomen, and thigh were reduced to 66% (P less than 0.001), 75% (P less than 0.01), and 72% (P less than 0.001) of their pretreatment values. The mean hair shaft diameters were reduced to 83% (P less than 0.0...

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Publication status:
Published

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Publisher copy:
10.1210/jcem-68-5-966
Journal:
Journal of clinical endocrinology and metabolism More from this journal
Volume:
68
Issue:
5
Pages:
966-970
Publication date:
1989-05-01
DOI:
EISSN:
1945-7197
ISSN:
0021-972X
Language:
English
Keywords:
Pubs id:
pubs:4303
UUID:
uuid:b7e38a17-ff27-47e9-be3f-35732a2cd5ba
Local pid:
pubs:4303
Source identifiers:
4303
Deposit date:
2012-12-19

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