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Gatifloxacin versus ofloxacin for the treatment of uncomplicated enteric fever in Nepal: an open-label, randomized, controlled trial

Abstract:

BACKGROUND: Fluoroquinolones are the most commonly used group of antimicrobials for the treatment of enteric fever, but no direct comparison between two fluoroquinolones has been performed in a large randomised trial. An open-label randomized trial was conducted to investigate whether gatifloxacin is more effective than ofloxacin in the treatment of uncomplicated enteric fever caused by nalidixic acid-resistant Salmonella enterica serovars Typhi and Paratyphi A. METHODOLOGY AND PRINCIPAL FIND...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher:
Public Library of Science
Journal:
PLoS Neglected Tropical Diseases More from this journal
Volume:
7
Issue:
10
Pages:
e2523
Publication date:
2013-10-31
Acceptance date:
2013-09-25
DOI:
EISSN:
1935-2735
ISSN:
1935-2727
Language:
English
Keywords:
UUID:
uuid:b7bc8743-5353-48f3-be49-3317d31141c7
Local pid:
pubs:440309
Source identifiers:
440309
Deposit date:
2014-02-08

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