Journal article icon

Journal article

Interferon, β-2-microglobulin and immunoselection in the pathway to malignancy. A blinkered view from Nag's Head Yard

Abstract:
Recent clinical studies suggest that benign tumour cells express MHC class-I antigens while malignant cells with the same tissue origin do not. Interferons induce normal cells to increase the expression of class-I antigens but Arnold Sanderson and Peter Beverley argue here that malignant cells may not respond in this way. As a result, they may lack the antigens that would make them vulnerable to immune mechanisms dependent on T cells which recognize class-I self-MHC antigens. © 1983.

Actions


Access Document


Journal:
Immunology Today More from this journal
Volume:
4
Issue:
8
Pages:
211-213
Publication date:
1983-01-01
DOI:
ISSN:
0167-5699
Language:
English
Pubs id:
pubs:94225
UUID:
uuid:b7b33358-ccb7-43f5-845b-aa977381a2cc
Local pid:
pubs:94225
Source identifiers:
94225
Deposit date:
2012-12-20

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP