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ETV6/RUNX1 fusion at diagnosis and relapse: some prognostic indications.

Abstract:

This study was undertaken in order to compare the interphase and metaphase cytogenetics of 28 patients with ETV6/RUNX1 positive acute lymphoblastic leukemia, at diagnosis and relapse. The median time to relapse was 26 months. The significant fusion positive population heterogeneity revealed at interphase by a commercial probe for ETV6/RUNX1 fusion has not been described before. Six diagnostic samples had a single abnormal population; others had up to five each, which differed in the numbers o...

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Publication status:
Published

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Publisher copy:
10.1002/gcc.20158

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Journal:
Genes, chromosomes and cancer
Volume:
43
Issue:
1
Pages:
54-71
Publication date:
2005-05-01
DOI:
EISSN:
1098-2264
ISSN:
1045-2257
Source identifiers:
39453

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