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CD8+ tumour-infiltrating lymphocytes in relation to HPV status and clinical outcome in patients with head and neck cancer after postoperative chemoradiotherapy: A multicentre study of the German cancer consortium radiation oncology group (DKTK-ROG).

Abstract:

We examined the prognostic value of tumour-infiltrating lymphocytes (TILs) in patients with squamous cell carcinoma of the head and neck (SCCHN) after surgery and postoperative cisplatin-based chemoradiotherapy. FFPE-tissue originating from the surgery of 161 patients treated in 8 DKTK partner sites was immunohistochemically stained for CD3 and CD8. Their expression was correlated with clinicopathological characteristics as well as overall survival (OS), local progression-free survival (LPFS)...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/ijc.29683

Authors


Publisher:
Wiley
Journal:
International journal of cancer. Journal international du cancer More from this journal
Volume:
138
Issue:
1
Pages:
171-181
Publication date:
2016-01-01
DOI:
EISSN:
1097-0215
ISSN:
0020-7136
Language:
English
Keywords:
Pubs id:
pubs:534344
UUID:
uuid:b7a31fd4-536a-48ed-a0ec-f103adc8fd77
Local pid:
pubs:534344
Source identifiers:
534344
Deposit date:
2015-11-23

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