Four independent structures of human interleukin-4, two determined by nuclear magnetic resonance techniques and two by X-ray diffraction, have been compared in detail. The core of this four helix bundle protein is very similar in all the structures but there are some differences in loop regions that are known to be mobile in solution. Careful comparison of the experimental data sets and the methods of analysis of the different laboratories has provided clues to the sources of most of the diff...Expand abstract
- Publication status:
- Publisher copy:
- Copyright date:
Comparison of four independently determined structures of human recombinant interleukin-4.
If you are the owner of this record, you can report an update to it here: Report update to this record