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Angiogenic capacity of endothelial cells in islets of Langerhans.

Abstract:

Transplantation of pancreatic islets reconstitutes glucose homeostasis in diabetes mellitus. Before transplantation, islets are disrupted from the surrounding blood vessels by the isolation procedure, with the grafted tissue being subject to ischemic damage. The survival of transplanted islets is assumed to depend on effective revascularization. Perfusion studies suggest that newly formed microvessels supplying the graft with nutrients are exclusively rebuilt by the host. It is generally not ...

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Publisher copy:
10.1096/fj.02-0615fje

Authors


Schneider, K More by this author
Hammes, HP More by this author
Preissner, KT More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences
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Journal:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Volume:
17
Issue:
8
Pages:
881-883
Publication date:
2003-05-05
DOI:
EISSN:
1530-6860
ISSN:
0892-6638
URN:
uuid:b6d5a352-856d-4f6e-a7a1-8cadf7da2e45
Source identifiers:
401691
Local pid:
pubs:401691

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