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Journal article

Ion channels: structure of a molecular brake

Abstract:

A combination of crystallographic and mutagenesis studies on the HERG K+ channel, a key determinant of cardiac excitability, has suggested how the protein's extramembraneous amino-terminal domain might act as a ‘molecular brake’ that slows down channel deactivation.

Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/S0960-9822(99)80106-7

Authors

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Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Role:
Author


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Funding agency for:
Sansom, M


Publisher:
Elsevier
Journal:
Current Biology More from this journal
Volume:
9
Issue:
5
Pages:
R173-R175
Publication date:
1999-03-01
Edition:
Publisher's version
DOI:
ISSN:
0960-9822


Language:
English
Subjects:
UUID:
uuid:b6d05581-08d6-460c-ac54-1c49ffcd405a
Local pid:
ora:8240
Deposit date:
2014-03-24
ARK identifier:

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