Journal article icon

Journal article

Tandem catalysis in the polycyclisation of dienes to produce multi-substituted tetrahydrofurans

Abstract:

A new catalytic protocol has been established by using two separate oxidation reactions, catalysed by osmium, in tandem. Control of the pH and oxidation state of the metal is crucial in controlling this new sequence, which begins with a tethered aminohydroxylation reaction (Os(VIII) is active) and is followed by an oxidative cyclisation under acidic conditions (Os(VI) is active). The result of this work is an extremely quick route (five steps from commercially available materials) to complex ...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author
Journal:
TETRAHEDRON LETTERS
Volume:
50
Issue:
26
Pages:
3523-3526
Publication date:
2009-07-01
DOI:
ISSN:
0040-4039
Source identifiers:
41240
Language:
English
Keywords:
Pubs id:
pubs:41240
UUID:
uuid:b69e0d2f-a8e0-46fe-b96a-13b6f74945ec
Local pid:
pubs:41240
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP