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Journal article

Mechanisms of disease: L-arginine in coronary atherosclerosis--a clinical perspective.

Abstract:

L-arginine is the substrate of endothelial nitric oxide synthase and the main precursor of nitric oxide in the vascular endothelium, thus its effects are mediated largely by increases in nitric oxide production. L-arginine has antioxidant and antiapoptotic properties, increases smooth muscle relaxation, inhibits the expression of adhesion molecules and chemotactic peptides, decreases endothelin-1 expression, and inhibits platelet aggregation. This amino acid also improves endothelial function...

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Publisher copy:
10.1038/ncpcardio0878

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Journal:
Nature clinical practice. Cardiovascular medicine
Volume:
4
Issue:
5
Pages:
274-283
Publication date:
2007-05-01
DOI:
EISSN:
1743-4300
ISSN:
1743-4297
Source identifiers:
223241
Language:
English
Keywords:
Pubs id:
pubs:223241
UUID:
uuid:b68b2132-6b02-4fd6-a037-5a3ba6872589
Local pid:
pubs:223241
Deposit date:
2012-12-19

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