Journal article
Abdominal aortic aneurysm is associated with a variant in low-density lipoprotein receptor-related protein 1.
- Abstract:
-
Abdominal aortic aneurysm (AAA) is a common cause of morbidity and mortality and has a significant heritability. We carried out a genome-wide association discovery study of 1866 patients with AAA and 5435 controls and replication of promising signals (lead SNP with a p value < 1 × 10(-5)) in 2871 additional cases and 32,687 controls and performed further follow-up in 1491 AAA and 11,060 controls. In the discovery study, nine loci demonstrated association with AAA (p < 1 × 10(-5)). In th...
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- Publisher copy:
- 10.1016/j.ajhg.2011.10.002
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Authors
Bibliographic Details
- Journal:
- American journal of human genetics
- Volume:
- 89
- Issue:
- 5
- Pages:
- 619-627
- Publication date:
- 2011-11-01
- DOI:
- EISSN:
-
1537-6605
- ISSN:
-
0002-9297
- Source identifiers:
-
415831
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:415831
- UUID:
-
uuid:b6774166-a471-41d6-845d-e6a7c9bb5b32
- Local pid:
- pubs:415831
- Deposit date:
- 2013-11-16
Terms of use
- Copyright date:
- 2011
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