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Evidence base of clinical diagnosis: Designing studies to ensure that estimates of test accuracy are transferable

Abstract:
There is merit in studies with heterogeneous study populations. They allow exploration of the extent to which the performance of a diagnostic test depends on prespecified predictors, and how much residual variation exists. The more variation there is in study populations, the greater the potential to know how the test will perform in various settings.

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Authors


Bossuyt, P More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Primary Care Health Sciences, PHC-CTU
Gatsonis, C More by this author
Journal:
British Medical Journal
Volume:
324
Issue:
7338
Pages:
669-671
Publication date:
2002-03-16
ISSN:
0959-8146
URN:
uuid:b6380316-2e92-49f8-91fc-8fb5a6b775da
Source identifiers:
215696
Local pid:
pubs:215696
Language:
English

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